PENGARUH PEMBERIAN JAMUR KUPING HITAM (Auriculariapolytricha) TERHADAP KADAR KOLESTEROL TOTAL, LDL (Low Density Lipoprotein), dan HDL (High Density Lipoprotein) SERUM TIKUS WISTAR YANG DIINDUKSI MINYAK JELANTAH

Budinastiti, Ratih and Sunoko Abdurachim, Henna Rya and Widyastiti, Nyoman Suci (2016) PENGARUH PEMBERIAN JAMUR KUPING HITAM (Auriculariapolytricha) TERHADAP KADAR KOLESTEROL TOTAL, LDL (Low Density Lipoprotein), dan HDL (High Density Lipoprotein) SERUM TIKUS WISTAR YANG DIINDUKSI MINYAK JELANTAH. Undergraduate thesis, Diponegoro University.

[img]
Preview
PDF
526Kb
[img]
Preview
PDF
118Kb
[img]
Preview
PDF
665Kb
[img]
Preview
PDF
237Kb
[img]PDF
Restricted to Registered users only

258Kb
[img]PDF
Restricted to Registered users only

298Kb
[img]
Preview
PDF
88Kb
[img]
Preview
PDF
2089Kb

Abstract

Background:The usage of reused cooking oil affects the increase of serumtotal cholesterol (TC) and LDL, also the decrease of serumHDL. This condition escalatesthe risk of atherosclerosis, which couldlead to the incidence of cardiovascular disease. Cloud ear fungus is a natural antioxidant that contains polysaccharides, flavonoids, niacin, and vitamin C, which can improve the lipid profiles. Objective: To analyze the impact of water from boiled cloud ear fungus on total cholesterol, LDL, and HDL level of Wistar ratsthat have been given reused cooking oil. Methods:This study is a true experimental research with post test only control group design, using 12 weeks-aged male Wistar rats (n = 24) that were randomly divided into 4 groups. K1 as the negative control, K2 was given reused cooking oil and standard diet, K3 was given water from boiled cloud ear fungus and standard diet, and K4 was given reused cooking oil, water from boiled cloud ear fungus and standard diet. Serum total cholesterol, LDL, and HDL levels were measured by the CHOD-PAP method after 28 days treatment. Results:TC mean value of K1 (80.2217 ± 3.61 mg / dL), K2 (195.8483 ± 5.47 mg / dL), K3 (75.5800 ± 4.02 mg / dL), and K4 ( 110.8683 ± 5.82 mg / dL); p = 0.000. LDL mean value of K1 (29.9200 ± 1.53 mg / dL), K2 (78.4167 ± 1.77 mg / dL), K3 (24.3167 ± 1.77 mg / dL), and K4 (40, 1617 ± 2.84 mg / dL); p = 0.000. HDL mean value of K1 (65.8950 ± 1.99 mg / dL), K2 (24.3233 ± 1.44 mg / dL), K3 (73.2300 ± 1.92 mg / dL), and K4 (54 , 9550 ± 2.04 mg / dL); p= 0.000. Conclusion:Water from boiled cloud ear fungus decreases the serum total cholesterol and LDL, and increasesserum HDL levels ofWistar rats that has been given reused cooking oil. Keywords:cloud ear fungus, reused cooking oil, total cholesterol, LDL, HDL

Item Type:Thesis (Undergraduate)
Subjects:R Medicine > RS Pharmacy and materia medica
Divisions:Faculty of Medicine > Department of Medicine
Faculty of Medicine > Department of Medicine
ID Code:50816
Deposited By:Ms Lutfiatun Heni
Deposited On:17 Nov 2016 10:44
Last Modified:17 Nov 2016 10:44

Repository Staff Only: item control page