PENGARUH PEMBERIAN ASAP CAIR PADA BERBAGAI KONSENTRASI TERHADAP PERTUMBUHAN Porphyromonas gingivalis PENYEBAB NEKROSIS PULPA

Abstract

Background: The most prevalent etiology of pulp disease is iritants, caused by microorganism invasion or its product through the break of dentin. Pulp infections are generally polymicrobial, which is caused by many kinds of bacteria, dominated by anaerobic bacteria. Porphyromonas gingivalis is one of the examples. Liquid smoke has antibacterial effect due to its components, such as organic acid, phenol, and carbonyl. Aim: To know the influence of liquid smoke in various concentrations on the growth of Porphyromonas gingivalis which causes pulp necrosis. Methods: This research was an experimental laboratory research with post test only control group design. The sample in this research was Porphyromonas gingivalis colony with six different concentrations of liquid smoke (100%,50%,25%,12.5%, and 6.25%), and the duplication was five times. Result: Kruskal-Wallis test on MIC data analysis showed that there was a significant difference (p=0.000), as well as the MBC data analysis (p=0.001). Then, it continued with Mann-Whitney test which also showed that there was a significant difference on P6 (0%) group. The lowest concentration which could kill the bacteria was 6.25%. Conclusion: Liquid smoke has influenced the growth of Porphyromonas gingivalis, with which The Minimum Inhibitory Concentration (MIC) and the Minimum Bactericidal Concentration (MBC) is 6.25%. Keywords: Liquid smoke, Pulp necrosis, Porphyromonas gingivalis, MIC, MBC.