PENGARUH PENGGUNAAN NIFEDIPIN PADA PENDERITA HIPERTENSI TERHADAP LAJU ALIRAN SALIVA DAN PEMBESARAN GINGIVA

Abstract

Background : The prevalence of hypertension is increasing in society. Nifedipine as one of antihypertensive drugs from Calcium Channel Blocker is the type of drug that is often used . The impact on the oral cavity due to the use of nifedipine in patients with hypertension can cause gingival enlargement and reduction in salivary flow . Aim : This research was to prove the influence of nifedipine on gingival enlargement and salivary flow. Method : This study is using observational analytic design with cross sectional approach. The required number of subjects in the study were 70 people who were divided into nifedipine-users group and control group. Subjects were conducted with consecutive sampling method. Gingival enlargement is measured vertically and horizontally using a periodontal probe. Saliva was conducted using passive drool for 1 minute. Result : Mann Whitney test can be concluded that there is a significant difference for gingival enlargement and salivary flow rate between nifedipine user groups and the control group ( p < 0,05 ). Conclusion : There is a significant relationship to gingival enlargement and salivary flow rate per minute between hypertensive patients who use nifedipine and do not use nifedipine. Keywords : Hypertension, nifedipine, salivary flow rate, gingival enlargemet