Correlation Between Number of Leucocyte and CRP Levels with Infarct Volume of Acute Ischaemic Stroke

Abstract

Aim: To determinethe correlation between the inflammatory response with the size of the infarct of the first acute ischemic stroke. Study design:Cross sectional study. Methods: Blood samples were taken in the ward.Ct scan was performed when the patient entered emergency room. Infarct volume measured by manual tracing perimeter infarct. The correlation analysis used various statistical tests and multivariate tests with logistic regression. Results: Obtained subject as many as 43 sample. The mean of infarct volumewas3.046.95cm3, leukocytes was1,0120.53,444.9 / mm3 and hsCRPwas2.495.3mg / dL. Thereisa positive correlation between leukocyte count and infarct volume but the Correlationis weak, whereas CRP levels with infarct volume showed a positive and significant Correlation. Multivariate test for risk factor resulted in correlation between CRP and BMI levels with infarct volume but only CRP showed significant correlation (p = 0.022). Conclusions: There is a weak positive correlation between the number of leukocytes and the volume of acute stroke infarction. There is a significant correlation between CRP levels and the volume of acute stroke infarction. Keywords: number of leukocytes, CRP levels, infarct volume