BEBERAPA FAKTOR RISIKO KEJADIAN HEPATITIS B KRONIK (Studi Kasus-Kontrol di RSUP Dr. Wahidin Sudirohusodo Makassar)

FAISAL, Faisal and Hadisaputro, Soeharyo and Purnomo, Hery Djagat (2016) BEBERAPA FAKTOR RISIKO KEJADIAN HEPATITIS B KRONIK (Studi Kasus-Kontrol di RSUP Dr. Wahidin Sudirohusodo Makassar). Masters thesis, Program of Postgraduate.

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Abstract

Latar Belakang: Data Kemenkes tahun 2011 prevalensi hepatitis B di Indonesia sebesar 30 juta, termasuk peringkat ketiga di dunia. Sekitar 70% hepatitis B kronik bersifat asimtomatik, berpotensi menular dan berkembang menjadi sirosis, kanker hati, dan menyebabkan kematian. Faktor host dan environment berkaitan erat dengan infeksius dan kronisitas kejadian hepatitis B kronik. Tujuan penelitian untuk membuktikan berbagai faktor host dan environment yang merupakan faktor risiko terhadap kejadian hepatitis B kronik. Metode: Penelitian ini menggunakan pendekatan mix method dengan desain studi case-control dan didukung wawancara mendalam. Populasi studi adalah pasien RSUP Dr. Wahidin Sudirohusodo Makassar yang diperoleh dari data rekam medis dan hasil pemeriksaan HBsAg. Sebanyak 176 orang sampel terdiri dari 88 kasus dan 88 kontrol secara consecutive sampling dengan matching pada jenis kelamin dan usia. Hasil: Berbagai faktor risiko yang terbukti berpengaruh terhadap kejadian hepatitis B kronik adalah (1) adanya riwayat keluarga penderita hepatitis B (aOR=14,3; 95%CI=4,28-48,16), (2) penggunaan sikat gigi bersama (aOR=4,4; 95%CI=1,84-10,85), (3) kebiasaan hubungan seks bebas >1 pasangan (aOR=3,9; 95%CI=1,64-9,71), (4) konsumsi ballo/alkohol >1 gelas/konsumsi (aOR=2,3; 95%CI=1,08-5,13), dan (5) penggunaan pemotong kuku bersama (aOR=2,3; 95%CI=1,12-4,80). Simpulan: Probabilitas kejadian hepatitis B kronik jika ada riwayat keluarga penderita hepatitis B, menggunakan sikat gigi bersama, berhubungan seks bebas >1 pasangan, mengkonsumsi ballo/alkohol >1 gelas/konsumsi, dan menggunakan pemotong kuku bersama adalah sebesar 82,7%. Kata kunci : Hepatitis B kronik, Faktor risiko Background: Ministry of Health data in 2011 shows that the prevalence of hepatitis B in Indonesia was 30 millions and become the third highest in the world. About 70% of chronic hepatitis B was asympotmatic, potentially infectious and lead to cirrhosis, liver cancer, and death. Host and environmental factors were closely related to infectivity and chronicity of Hepatitis B incidence. The research aims to proved variety of host factors and environmental factors of chronic hepatitis B incidence. Methods: This research used a mix method with case-control design study approach and was supported by in depth interview. The study population was patients from Dr. Wahidin Sudirohusodo Central Hospital which were obtained from medical records and HBsAg test result. There were 176 patients recruited from 88 in case group and 88 in control group, by using consecutive sampling with gender and age matching process. Results: Risk factors approverd for chronic hepatitis B incidence were the family history of hepatitis B patients (aOR=14.3; 95%CI=4.28-48.16), shared toothbrush using (aOR=4.4; 95%CI=1.84-10.85), free sex habit (aOR=3.9; 95%CI=1.64-9.71), ballo/alcohol consuming >1 cup/consumption (aOR=2.3; 95%CI=1.08-5.13), and shared nail clipers using (aOR=2.3; 95%CI=1.12-4.80). Conclusion: Event probability for chronic hepatitis B incidence when the all five risk factors happened namely family history of hepatitis B patients, shared toothbrush using, free sex habit, ballo/alcohol consuming >1 cup/consumption, and shared nail clipers using was 82.7%. Key words: Chronic Hepatitis B, Risk Factors

Item Type:Thesis (Masters)
Subjects:R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions:School of Postgraduate (mixed) > Master Program in Epidemiology
ID Code:75023
Deposited By:Mrs Ekana Perpus Pasca
Deposited On:02 Aug 2019 10:45
Last Modified:02 Aug 2019 10:45

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