PENDETEKSIAN KELAINAN FUNGSI GINJAL DENGAN MEMANFAATKAN RADIOFARMAKA HIPPURAN I131 MENGGUNAKAN KAMERA GAMMA

Abstract

Have been done detection of disparity of kidney function by exploiting radiopharmaceutical Hippuran I131 in kidney inspection (renogram) used the radioisotope I131 which have half live 8,04 days and transmit gamma rays. Radioisotope I131 were inseminated through intravenous. The substance will be filtered by glomerulus and be secreted by tubulus kidney, and released almost entirety from kidney. Radiopharmaceutical will be detected by detector of gamma camera and presented to the monitor in the form of kidney picture and will be analysed by computer to know the existence of disparity of kidney function. The result was obtained from inspection two patients, one of patient, both of kidneys is normal function. The effective renal plasma flow of right kidney is equal whit left kidney that is 143 ml / minute. This assess come near to normal that is 120 ml / minute. At second patient, the right kidney is normal function, the graph obtained had the same pattern tendency with the normal kidney graph. While for the left kidney only permeate a little radiopharmaceutical so that the left kidney picture is invisible in image result, the graph increase only a little above background. The effective renal plasma flow of right kidney is 285 ml / minute and the left kidney is 0 ml / minute. This matter show that the left kidney is functionally not function. Keywords; Hippuran, Radioisotope, Radiopharmaceutical, detector of gamma camera