Two new compounds from an Indonesian spons Dysidea sp.

Trianto, Agus and Voogd, N.J.D and Tanaka, Junichi Two new compounds from an Indonesian spons Dysidea sp. Jurnal Journal of Asian Natural Product Research , 16 (2). pp. 163-168. ISSN 10286020

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Official URL: http://www.tandfonline.com/loi/ganp20

Abstract

n our joint bioprospecting research on Indonesian marine invertebrates, we found moderate cytotoxicity on an extract of the sponge Dysidea sp. collected at Biak, West Papua. Separation of the extract provided two new compounds, biaketide (1) and debromoantazirine (2), along with four known molecules 3–6. The new structures were elucidated by spectroscopic analyses and by comparison with those reported. Compounds 1 and 2 showed moderate cytotoxicity against NBT-T2 cells with IC values of 8.3 and 4.7 mgml 21, respectively.

Item Type:Article
Subjects:Q Science > Q Science (General)
Divisions:Faculty of Fisheries and Marine Sciences > Department of Marine Science
ID Code:64932
Deposited By:MS. Bahry
Deposited On:18 Sep 2018 23:30
Last Modified:06 Dec 2019 11:01

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