Novel Archaeal DNA Polymerase B from Domas Hot Spring West Java

Suharti, S. and Hertadi, Rukman and Warganegara, Fida Madayanti and Nurbaiti, Santi and Akhmaloka, A. (2015) Novel Archaeal DNA Polymerase B from Domas Hot Spring West Java. In: The 5th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application (5th ISNPINSA) i , 7-8 Oktober 2015, Semarang.

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Abstract

Nine novel archaeal DNA polymerase genes from Domas Hot Spring, West Java have been cloned directly through the natural sample. The characterization of the genes showed that the genes are high homology to the DNA polymerase B of Crenarhaea phyla. Phylogenetic analysis of the amino acid sequences showed that the enzymes are grouped in a new branch from the other Crenarchaea’s DNA Polymerase B. 3D structure analysis of the enzymes show that the structures are closed to the structure of DNA Polymerase B1 from Sulfolobus solfataricus. The nine structures of the enzymes could be grouped into four different structures.

Item Type:Conference or Workshop Item (Paper)
Subjects:Q Science > Q Science (General)
Divisions:Faculty of Science and Mathematics > Department of Chemistry
ID Code:62540
Deposited By:Faculty of Engineering
Deposited On:28 May 2018 09:08
Last Modified:28 May 2018 09:08

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