Genetic diversity at the FMR1 locus in the Indonesian population

Faradz, Sultana M.H. and Pattiiha, M Z and Leigh, D A and Jenkins , M and Leggo, J and Buckley, Michael F and Holden, J J A (2000) Genetic diversity at the FMR1 locus in the Indonesian population. Annals of Human Genetics , 64 (04). pp. 329-333.

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We report an analysis of allelic diversity at short tandem repeat polymorphisms within the fragile XA locus in 1069 male volunteers from twelve Indonesian sub-populations. An odd numbered allele of DXS548 was found at high frequency in all Indonesian populations. Greater allelic diversity was identified at the loci under study than has been previously reported for an Asian population. These differences distinguish the Indonesian population from all previously reported Asian, European and African populations. A high frequency of small premutation alleles, 4/120 (3.3%, 95% CI 0.9–8.3%), was identified in the Moluccan population of Hiri Island.

Item Type:Article
Subjects:Q Science > QH Natural history > QH426 Genetics
Divisions:Faculty of Medicine > Department of Medicine
Faculty of Medicine > Department of Medicine
ID Code:543
Deposited By:Mr. Sugeng Priyanto
Deposited On:09 Sep 2009 14:34
Last Modified:09 Sep 2009 14:34

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