HUBUNGAN ANTARA STATUS DIABETES MELITUS TIPE 2 DENGAN STATUS TUBERKULOSIS PARU LESI LUAS

Abstract

Background : Pulmonary tuberculosis (pulmonary TB) is a contagious infection disease caused by the Mycobacterium tuberculosis bacteria and until now remains as the health issue in the world, especially in the developing countries. One of the tuberculosis risk factors is diabetes mellitus. DM patients have the risk of getting TB 2 or 3 times compare with the non-DM individuals. Objective : Analyze the relations between the DM type 2 and the advance lesion pulmonary tuberculosis status. Method : This study was an observational analytic research with cross sectional study design. There were 43 samples of tuberculosis patients which were treated in BKPM Semarang. The variables were measured through blood sugar levels inspection procedures and were conducted using Oral Glucose Tolerance Test(OGTT), x-ray examinations, interviews and medical records. The confounding variables in this research were smoking habits, nutritional status, housing conditions, socio-economic status, gender and age. Statistical analysis was performed using Chi-Square test and Mann-Whitney for bivariate. As for multivariate, logistic regression test was used. Results : The results showed that there was a significant relationship between type 2 diabetes mellitus with advance lesion pulmonary tuberculosis (p=0.03). Diabetes mellitus type 2 could increase the risk of advance lesion pulmonary tuberculosis as much as 5.25 times. The significant confounding variables in this research were smoking habits (p=0.01) and nutritional status (p=0.02). Conclusions : There was a significant relationship between diabetes mellitus type 2 and advance lesion pulmonary tuberculosis. Keyword : Lung tuberculosis, diabeetes melitus type 2, advance lesion.