HUBUNGAN ANTARA DISLIPIDEMIA DENGAN STATUS PENYAKIT ARTERI PERIFER (PAP) PADA PASIEN DIABETES MELITUS TIPE 2 TERKONTROL SEDANG

Abstract

Background: Peripheral arterial disease (PAD) is a disorder of the blood supply in the extremities due to obstruction caused by atherosclerosis. Patients with PAD have a greater risk of death from stroke, myocardial infarction and heart attacks. Diabetes mellitus and dyslipidemia are risk factors that are common in PAD. There has been no research on the correlation between dyslipidemia and PAD status in patients with moderate glycemic control type II DM. Objective: To analyze the correlation between dyslipidemia and PAD status in patients with moderate glycemic control type II DM. Methods: This study was an observational analytic research with cross sectional design used consecutive sampling method. There were 30 subjects with moderate glycemic control type II DM, 21 subjects with dyslipidemia, 9 subjects without dyslipidemia at ages ranging from 46 to 71 years. This study used primary and secondary data. PAD status was determined by examining Ankle Brachial Index (ABI) used a stethoscope at rest and post exercise if necessary. Statistical test used Chi-Square test, independent t test and logistic regression. Results: There were 12 subjects with PAD (40%). Chi-square test showed there was a significant correlation between the status of dyslipidemia with PAD status in patients with moderate glycemic control type II DM (p <0.025). The independent t test showed there was a significant difference between the levels of total cholesterol, LDL, HDL, and triglycerides in subjects with positive and negative PAD. The majority of subjects taking diabetic therapy regularly and some subjects also have hypertension. Conclusion: There was a significant correlation between dyslipidemia with PAD status in patients with moderate glycemic control type II DM. Keywords: diabetes mellitus, dyslipidemia, peripheral arterial disease