KUANTITAS PENGGUNAAN ANTIBIOTIK SEBELUM DAN SETELAH PEMBUATAN PEDOMAN PENGGUNAAN ANTIBIOTIK (PPAB)

Abstract

Background Pedoman Penggunaan Antibiotik (PPAB) is a book containing procedures and guides for using antibiotic properly. After the new revision, antibiotic prescription is expected to be proper with the written guidelines. Aim To measure quantity of antibiotic use in digestive cases before and after the making of PPAB. Methods This study is a prospective observational study. Subjects were patients in digestive surgery case hospitalizing in September and November. The use of antibiotic is compared between period of before and after the making of PPAB (October) using independent t test and Mann-Whitney test. Result DDD/100 patient days of antibiotic prophylaxis before the making of PPAB is 13,54 decrease to 11,96 after the making of PPAB, but the decrease is not significantly different in statistic test. The most antibiotic prophylaxis (ceftriaxone) before the making of PPAB (13,13 DDD/100 patient days) declined (11,18 DDD/100 patient days) after the making of PPAB. Quantity of antibiotic prophylaxis use of sefazolin before the making of PPAB is 0,42 DDD/patient days increase to 0,78 DD/100 patient days after the making of PPAB. Conclusion There is no significant changes of quantity of antibiotic cefazolin-ceftriaxone for prophylaxis in digestive surgical case between before and after the making of PPAB. Needed socialization, education, and training. Keywords Quantity of antibiotic use, Surgery Ward, Digestive Cases, Antibiotic Guideline.