PERBEDAAN DIAMETER LUMEN ARTERI UMBILIKALIS PADA PREEKLAMPSIA BERAT DAN KEHAMILAN NORMOTENSI

Abstract

Background : There were three main causes of death that increase morbidity and mortality of mother and fetus; infections ( 11 % ) , bleeding ( 27 % ) and preeclampsia ( 14 % ) . A form of defense against hemodynamic changes in preeclampsia, triggered a hypoplastic mechanism and increased the vascular morphology modification of umbilical blood vessels, includes the changes of umbilical arteries luminal diameter. Aim : To observe the difference of umbilical artery luminal diameter in severe preeclampsia and normotensive pregnancy Method : This was an analytic observational study with cross sectional design. Research subjects were pregnancy women aterm (37-42 weeks) in severe preeclampsia as a case group (n=16) and normotensive pregnancy for control (n=16), who treated at Department of Obstetri and Gynecology in Dr Kariadi Semarang Hospital during this research period. The data was taken by purposive sampling then measured with microscope dot slide. The hypothesis was analyzed with Mann-Whitney test. Results : The umbilical artery luminal diameter in severe preeclampsia was increased compared to subjects who were in normotensive pregnancy. The umbilical artery lumen diameter median in severe preeclampsia is 1103 μm with 462 μm was the lowest score and 3913 μm was the highest score, and the median of umbilical artery lumen diameter in normotensive pregnancy was 779 μm with 601 μm was the lowest score and 2068 μm was the highest. The analysis showed p<0,05 (significance) for the difference of umbilical artery luminal diameter in severe preeclampsia and normotensive pregnancy Conclusions : The study found the differences between the umbilical artery luminal diameter in severe preeclampsia and normotensive pregnancy, which the lumen diameter was increased in severe preeclampsia. Keywords : Diameter, luminal, artery, umbilical, preeklampsia, normotensive