FAKTOR RISIKO KEMATIAN BAYI BARU LAHIR DENGAN PENYAKIT MEMBRAN HIALIN YANG DIBERI CONTINUOUS POSITIVE AIRWAY PRESSURE (CPAP)

Abstract

Background. Newborns with hyaline membrane disease (HMD) were still able to experience death although they were given by continuous positive airway pressure (CPAP). Early diagnosis and detection of multiple factors asosiated to these incident could be used to prevent mortality in newborns with HMD were given CPAP. Aim. To determine low birth weight (LBW), infection, premature, began CPAP> 5 hours after birth, the degree of HMD, asphyxia, not given antenatal steroids and surfactant as factors assosiated to the mortality of newborns with HMD were given CPAP. Methods. An analytical observational study with case control design was conducted in Dr. Kariadi Hospital using medical records in January 2009 - December 2014. The group of 20 cases of newborns with HMD were given CPAP and died. The control group are newborns with HMD were given CPAP and survived as much as 20 babies. Subjects taken by consequtive sampling method. HMD was based on doctor's diagnosis and/or radiology. Bivariate analysis was done using Chi-square and Fisher Exact. Multivariate analysis was done using logistic regression. Results. Multivariate analysis found the factors that influence the mortality of newborns with HMD by CPAP is the severity of HMD (p=0,006; OR=4,666; 95%CI=1,568-13,888). Factors other than the severity of PMH does not become an influential factor. Conclusion. Severity factor of HMD was assosiated with mortality of newborns with HMD were given CPAP. Keywords: HMD, CPAP, mortality risk factors.