BEBERAPA FAKTOR RISIKO PASIEN YANG BERPENGARUH TERHADAP IN HOSPITAL MORTALITY PASIEN STROKE ISKEMIK (Studi Kasus di RSUP Dr. Kariadi)

LAYANTO, Agus (2014) BEBERAPA FAKTOR RISIKO PASIEN YANG BERPENGARUH TERHADAP IN HOSPITAL MORTALITY PASIEN STROKE ISKEMIK (Studi Kasus di RSUP Dr. Kariadi). Masters thesis, Program Pascasarjana UNDIP.

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Abstract

Latar Belakang : Stroke merupakan masalah kesehatan masyarakat yang penting. In hospital mortality merupakan salah satu ukuran dari ketahanan hidup pasien stroke. Riwayat hipertensi, diabetes, hiperkolesterolemia, penyakit jantung dipertimbangkan berpengaruh terhadap in hospital mortality pasien stroke, tetapi studi dengan mempertimbangkan kepatuhan berobat belum pernah dilakukan. Metode : Penelitian analitik observasional dengan rancangan kasus kontrol. Kasus adalah pasien stroke iskemik pertama kali, berusia ≥ 18 tahun dan meninggal selama dalam perawatan di RSUP Dr.Kariadi sedangkan kontrol adalah pasien yang tidak meninggal, sebanyak 33 kasus dan 33 kontrol. Data diperoleh dari register rawat inap, catatan medis dan wawancara. Data diolah dengan menggunakan program SPSS for Windows versi 17.0. Uji chi-square untuk variabel nominal, uji t tidak berpasangan/uji Mann-Whitney untuk variabel numerik pada analisis bivariat dan regresi logistik pada analisis multivariat, penghitungan OR untuk mengetahui besarnya risiko. Hasil : Faktor risiko yang terbukti berpengaruh terhadap kejadian in hospital mortality pasien stroke iskemik adalah kepatuhan pengobatan hipertensi (OR 5,5; p=0,009; 95% IK 1,5-20,2), kepatuhan pengobatan diabetes (OR 4,1; p=0,038; 95% IK 1,1-15,5) dan aktivitas fisik (OR 4,1; p=0,028; 95% IK 1,2-14,3). Faktor risiko yang tidak terbukti berpengaruh adalah usia, riwayat keluarga stroke, keberadaan asuransi, kepatuhan pengobatan hiperkolesterolemia, kepatuhan pengobatan penyakit jantung, waktu admisi dan tipe stroke iskemik. Simpulan : Kepatuhan pengobatan hipertensi, kepatuhan pengobatan diabetes dan aktivitas fisik merupakan faktor risiko yang berpengaruh terhadap in hospital mortality pasien stroke iskemik, dengan probabilitas sebesar 89%. Kata kunci : stroke iskemik, faktor risiko pasien, in hospital mortality, kasus kontrol Background : Stroke is one of the important public health problems. In hospital mortality is one of parameter for stroke patient survival. History of hypertension, diabetes, hypercholesterolemia, cardiac diseases were considered as factors that influence in hospital mortality in stroke patient, but study that considering drug compliance is absence. Methods : An observational analytic study with case control design was done. Cases are first-ever ischemic stroke patients, age ≥ 18 years old and died during admission in Kariadi Hospital, while controls are same with cases but had life at discharge, 33 cases and 33 controls were included. Data were accepted from admission register, medical record and interview. Data were computed with SPSS for Windows Release 17.0 software. Chi-square test for nominal variable, independent t-test/mann-whitney test for numeric variable in bivariate analysis and logistic regression in multivariate analysis, with OR for measure risk factors. Results : Risk factors that significantly influence in hospital mortality of ischemic stroke patient were hypertension compliance (OR 5,5; p=0,009; 95% CI 1,5-20,2), diabetes compliance (OR 4,1; p=0,038; 95% CI 1,1-15,5) and physical activity (OR 4,1; p=0,028; 95% CI 1,2-14,3). Other risk factors i.e. age, family history of stroke, insurance status, hypercholesterolemia compliance, cardiac diseases compliance, admission time and ischemic stroke type were not significantly influence. Conclusion : Hypertension compliance, diabetes compliance and physical activity are risk factors that influence in hospital mortality of ischemic stroke patient, with probability for occurence is 89%. Key words : ischemic stroke, patient risk factors, in hospital mortality, case control

Item Type:Thesis (Masters)
Subjects:R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions:School of Postgraduate (mixed) > Master Program in Epidemiology
ID Code:45313
Deposited By:Mrs Ekana Perpus Pasca
Deposited On:30 Mar 2015 11:38
Last Modified:30 Mar 2015 11:38

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