Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian

Issa, Hamad H. and Tanaka, Junichi and Rachmat, Rachmaniar and Setiawan, Andi and Trianto, Agus and Higa, Tatsuo (2005) Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian. Marine Drugs, 3 (3). pp. 78-83. ISSN 1660-3397

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Official URL: http://www.mdpi.com/1660-3397/3/3/78


Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compounds [1-5]. Compounds 1 and 2 are closely related to cylindricines A and B, lacking C-4 oxygenation found in cylindricines and having a butyl instead of a hexyl appendage. NOE experiments on compounds 1 and 2 suggested the A/B ring fusion to be cis.

Item Type:Article
Uncontrolled Keywords:polycitorols, Polycitoridae, tricyclic alkaloids, ascidian, polycyclic alkaloids
Subjects:G Geography. Anthropology. Recreation > GC Oceanography
Divisions:Faculty of Fisheries and Marine Sciences > Department of Marine Science
ID Code:430
Deposited By:Mr. Sugeng Priyanto
Deposited On:31 Aug 2009 10:12
Last Modified:31 Aug 2009 10:12

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