POTENSI TEH HIJAU (Camelia sinensis L.) DALAM PERBAIKAN FUNGSI HEPAR PADA MENCIT YANG DIINDUKSI MONOSODIUM GLUTAMAT (MSG)

Abstract

This study aimed to assess the condition of the liver histology in mice given the green tea MSG induced and analyze the potential of green tea (Camelia sinensis L.) in improving liver function in mice induced MSG. The study was conducted for 30 days with test animals such as male mice strain Balb/c. This study used a completely randomized design factorial. Each treatment consisted of P0 as controls who were given distilled water 0.5 ml/bb/day, which were given green tea P1 0.015 gr/bb/day, given P2 MSG 0.84 gr/bb/day, P3 given MSG 0, 84 gr/bb/day and green tea 0,015 gr/bb/day. The results showed that the induction dose of MSG 0.084 gr/bb/day have an impact on the decrease in liver weight, elevated levels of ALT and hepatocyte diameter. The administration of green tea dosage 0.015 gr/bb/day in mice MSG induced or without MSG induction can increase liver weight, decreased levels of ALT and hepatocyte diameter. Interaction of MSG and green tea occurs in hepatocytes diameter, so it can be concluded that the administration of green tea dosage 0.015 gr/bb/day is able to repair damage hepatocytes caused by MSG induction dose of 0.084 gr/bb/day.