KUANTITAS PENGGUNAAN ANTIBIOTIK DI BANGSAL BEDAH DAN OBSTETRI-GINEKOLOGI RSUP DR. KARIADI SETELAH KAMPANYE PP-PPRA

Abstract

Background Pilot Project-Program Pencegahan Pengendalian Resistensi Antibiotik (PP-PPRA) campaign aimed to promote prudent use of antibiotic to prevent from antibiotic resistance. After campaign, prudent use of antibiotic is expected to increase and quantity of antibiotic use is expected to decrease. Aim To measure quantity of antibiotic use in Surgery and Obstetric-Gynecology (Obgy) Ward after PP-PPRA campaign. Methods This study used observational analitic design with prospective approachment. Subjects were patients in Surgery and Obgy Ward with clean or clean contaminated surgery and ASA score I-II during January-July 2012. Antibiotic use was recorded from medical record. Analysis data was performed with independent t test and Mann-Whitney test. Results DDD/100 bed days in Surgery Ward (51.82) higher than that in Obgy Ward (46.7). Mean of DDD total antibiotic/day in Surgery Ward (0.53) higher than in Obgy Ward (0.46). The use antibiotic is not compatible with the antibiotic guideline (ceftriaxone) in surgery ward (36.9 DDD/100 bed days) is significantly higher than that in Obgy (5.67 DDD/100 bed days, p=0.00). The use of antibiotic compatible with the antibiotic guideline (cefazoline) in Obgy Ward (28.24 DDD/100 bed days)is significantly higher than that in Surgery Ward (4.33 DDD/bed days, p=0.00) Conclusion Quantity of antibiotic use in Surgery Ward is higher than that in Obgy Ward. Surgery ward used antibiotic which is not compatible with guideline more than Obgy Ward. Keywords Quantity of antibiotic use, Surgery Ward, Obstetric-Gynecology Ward, PP-PPRA campaign.