DISLIPIDEMIA PADA OBESITAS DAN TIDAK OBESITAS DI RSUP DR. KARIADI DAN LABORATORIUM KLINIK SWASTA DI KOTA SEMARANG

Abstract

Background: Obesity is a multifactorial disease and is a dangerous factor for the onset of serious diseases such as dyslipidemia, stroke, coronary heart disease, etc. Dyslipidemia is a disorder of lipid metabolism is marked increase in total cholesterol, LDL cholesterol, triglycerides and decreased HDL cholesterol in the blood. Shah SZA et al (2008), who have conducting research in Pakistan with majorities subjects from both sides (obesity and non obesity) in urban society. On comparation of lipid profile between two groups, average of total cholesterol not significantly different (P>0.05), and average value of total cholesterol per HDL, total LDL cholesterol and TG in group of obesity significantly different (P<0.05). Aim: Knowing the differences in lipid profiles between obesity and non obesity in the department of Dr. Kariadi and private clinical laboratories in the city of Semarang. Methods: This research is an analitical observation with cross sectional design. Samples on this research is based on medical record datas from patients with dyslipidemia with obesity and non obesity from more than 30 years old in RSUP dr. Kariadi and two clinical laboratories in Semarang, that observed between October 2011 until March 2012. The datas were process by using Chi square method. Results: This research is used 363 samples of hypercholesterolemia (p = 0.457), hypertriglyceridemia (p = 0.001), hypo-HDL in male gender (p = 0.010), hypo-HDL in the female sex (p = 0.097), hyper-LDL (p = 0.256), and mixed dyslipidemia (p = 0.069) Conclusion: Hypertriglyceridemia and hypo-HDL in male sex between obese and non obese, and found significant differences whereas hypercholesterolemia, hypo-HDL in the female sex, hyper-LDL, mixed dyslipidemia between the obese and non obese differences found but non-significant. Keywords: dyslipidemia, hypercholesterolemia, hyper-LDL, hypo-HDL, hypertriglyceridemia, obesity, non obesity