PERBANDINGAN RESPON KARDIOVASKULER ANTARA FENTANIL DAN KLONIDIN PADA TINDAKAN LARINGOSKOPI DAN INTUBASI ENDOTRAKEA

Abstract

Background: Airway management is an essential skill to be possessed by any anaesthesiologist. Laryngoscopy and endotracheal intubation are the most often way to maintain the airway. However ET intubation often cause an increasing blood pressure, heart rate, and cause arrhytmia. Administration of fentanyl and clonidine before ET intubation can reduce these elated cardiovascular responses. Aim: This study aimed to prove the difference between fentanyl 2 μg/kg intravenous and clonidine 2 μg/kg intravenous administration in reducing the cardiovascular responses due to laryngoscopy and ET intubation. Methods: An observational study with cross-sectional approach. Data were derived from secondary data with total sample of 48 patients which divided into two groups. Group 1 was patient who given fentanyl 2 μg/kg intravenously and Group 2 was given clonidine 2 μg/kg intravenously. Systolic and diastolic blood pressure, mean arterial pressure, and heart rate were recorded before intubation and in the first, third, and fifth minute after intubation. Results: In the first, third, and fifth minute after intubation showed no significant difference in systolic blood pressure, diastolic blood pressure, mean arterial pressure, and heart rate between Group 1 and Group 2 (p > 0,05). Conclusions: There is no significant difference between fentanyl 2 μg/kg intravenous and clonidine 2 μg/kg intravenous administration in reducing the cardiovascular responses due to laryngoscopy and ET intubation. Key words: cardiovascular response, laryngoscopy, ET intubation, fentanyl, clonidine xv