FAKTOR RISIKO TERJADINYA KOINFEKSI TUBERKULOSIS PADA PASIEN HIV/AIDS DI RSUP DR. KARIADI SEMARANG

Abstract

Background: Tuberculosis is the most common opportunistic infection disease among HIV/AIDS patient. HIV-TB coinfection is currently the world's leading cause of mortality due to infectious agent. Objective: To determine the risk factor of Tuberculosis coinfection among HIV/AIDS patient in Dr. Kariadi Hospital Semarang. Methods: This research is an analytical observational research with case control design, using medical records as samples. The samples consisted of 83 HIV/AIDS patients with Tuberculosis coinfection and 83 HIV/AIDS patient without Tuberculosis coinfection period January 2008- June 2012. Analysis data used Chi Square test. Results: On the whole study result showed that, group of man HIV-TB coinfected patient recorded the highest value, 59 respondents (71.1%), 15-35 years category recorded the highest number, 49 respondents (59%). Employed respondents were higher, 37 respondents (68.5%), which the most common type of job were housewife (10.8%) and unemployed (10.8). Ten to twelve g/dL hemoglobin level recorded the highest proportion (50.7%), CD4 count <100 cell/μL was the highest (87.3%). The highest number of tuberculosis site was pulmonary tuberculosis (89.2%), the negative sputum AFB smear examination was the highest (31.3%), and the most common comorbidity was the candidiasis oral (20.8%). Variable related to the TB coinfection among HIV/AIDS patient was the low hemoglobin level (p=0.001). Otherwise, sex, age, marital status, CD4 count, smoking, alcohol, and ARV therapy did not relate to TB coinfection among HIV/AIDS patient. Conclusion: According to the study, variable related to TB coinfection among HIV/AIDS patient was the low hemoglobin level that support the earlier studies. Otherwise, sex, age, marital status, CD4 count, smoking, alcohol, and ARV therapy did not relate to TB coinfection among HIV/AIDS patient. Keywords: TB, HIV, AIDS, risk factor, coinfection