UJI DIAGNOSTIK PROKALSITONIN DIBANDING KULTUR DARAH SEBAGAI BAKU EMAS UNTUK DIAGNOSTIS SEPSIS BAKTERIAL DI RSUP Dr.KARIADI

Abstract

Background: Sepsis is a serious health problem arround the world because the late diagnosis can threathen life. Diagnosis by blood culture as the gold standard need 2-3 days.A more rapid and accurate diagnostic method is needed This study aimed to determine sensitivity,spesificity,positive predictive value,and negative predictive value of Procalcitonin test compared to blood culture for diagnosis of bacterial sepsis. Methods: Data used in this study is patients diagnosed sepsis clinically in Kariadi hospital Semarang in 2011. Study subjects totaled 27 people aged less than 1 year till 87 years. Results of procalcitonin test with determined cut- off point compared with the blood culture results , then assess the diagnostic procalcitonin . Results: At 2 ng/ml obtained sensitivity 66,6%,spesificity 44,4%, positive predictive value 37,5%, negative predictive value 72,7%,and accuration 51,85%. Conclusion: The sensitivity,spesificity,positive predictive value,negative predictive value,and accuration of Procalcitonin test for diagnosing sepsis in Kariadi hospital are low. Keyword:Sepsis, Procalcitonin, blood culture.