HUBUNGAN ANTARA HASIL PEMERIKSAAN DARAH LENGKAP DENGAN DERAJAT KLINIK INFEKSI DENGUE PADA PASIEN DEWASA DI RSUP Dr. KARIADI SEMARANG

Abstract

Background: Complete blood count which is usually done to screen patients suspected dengue infection is through the examination including platelet count, leukocyte count, hematocrit, and hemoglobin levels. The existence of an exact value of the result of blood test for each grade of dengue infection is expected to greatly assist medical officers in order to more easily classify and manage patients based on the clinical grade. Aim: To determine the correlation between platelet count, leukocyte count, hematocrit, and hemoglobin levels with clinical dengue grade infection. Methods: This was retrospective observational analytic research with cross sectional approach. Samples were taken from medical records of patients admitted to adult dengue infection in Dr. Kariadi Hospital. Data that taken from medical records were age, sex, platelet count, leukocyte count, hematocrit, hemoglobin levels, and the degree of dengue infection according to WHO 2009 criteria. The statistical analysis used descriptive analysis and hypothesis test by using Spearman correlation with SPSS for Windows 18. Results: 114 adult dengue infection patients were included in this research. The analysis by Spearman correlation test found a significant weak negative correlation between platelet count with clinical dengue grade infection (p<0.001 ; r=-0.341), a significant weak positive correlation between leukocyte count with clinical dengue grade infection (p=0.033 ; r=0.2), there was no significant correlation between hematocrit with clinical dengue grade infection (p=0.606 ; r=0.049), and there was no significant correlation between hemoglobin levels with clinical dengue grade infection (p=0.759 ; r=0.029). Conclusions: There was a significant correlation between platelet count and leukocyte count with clinical dengue grade infection so that platelet count and leukocyte count may be considered to help determine the clinical grade of dengue infection. There was no significant correlation between hematocrit and hemoglobin levels with clinical dengue grade infection. Keywords: platelet count, leukocyte count, hematocrit, hemoglobin levels, clinical dengue grade infection