PERBANDINGAN KUALITAS HIDUP PASIEN EPILEPSI LOBUS TEMPORAL YANG BEBAS KEJANG DENGAN YANG TIDAK BEBAS KEJANG PASCA AMIGDALOHIPPOKAMPEKTOMI

Abstract

Background : Epilepsy surgery is a choice of treatment for epilepsy patients who are resistant to anti-epileptic drugs. Epilepsy surgery is successful if the patient’s quality of life improved or better than before surgery and it can reduce seizure frequency. Aim : Prove the existences of quality of life differences in seizure-free patients compared with not seizure-free temporal lobe epilepsy patients post-amygdalohippocampectomy. Methodes : This is an Observational study with Cross Sectional design. The quality of life were assessed with QOLIE-31 questionnaire, while the patient’s seizure-free condition were taken from medical records. Then quality of life of seizure-free temporal lobe epilepsy patients were compared with not seizure-free patients after amygdalohippocampectomy. The statistical tests used were unpaired t-test if the data was distributed normally, and Mann-Whitney test if the data was not distributed normally. Results : 31 patients, 21 were seizure free (Engel 1) and 10 were not seizure free (Engel 2, 3 and 4), who have met the inclusion and exclusion criteria were analyzed. Statistical test results obtained with the seizure worry p = 0.003, overall QOL p = 0.001, emotional well-being p <0.001, energy / fatigue p <0.001, cognitive p = 0.002, medication Effects p = 0.01 , Social function p <0.001 . So that there were significant differences in quality of life of seizure-free temporal lobe epilepsy patients compared with not seizure-free patients. Conclusion : The quality of life of seizure-free temporal lobe epilepsy patients were significantly higher than those who were not seizure free after amygdalohippocampectomy. Key Words : Quality of life, QOLIE-31, seizure-free, temporal lobe epilepsy, amygdalohippocampectomy.