HUBUNGAN ANTARA TERAPI KORTIKOSTEROID DENGAN KEJADIAN GLAUKOMA PADA ANAK DENGAN SINDROM NEFROTIK

WAHYUNI, ANDI SRI and Muryawan, M. Heru and Radityo S, Adhie Nur (2012) HUBUNGAN ANTARA TERAPI KORTIKOSTEROID DENGAN KEJADIAN GLAUKOMA PADA ANAK DENGAN SINDROM NEFROTIK. Undergraduate thesis, Fakultas Kedokteran.

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Abstract

Background: Nephrotic syndrome is one of the most found kidney disease in children and corticosteroids are the primary form of therapy. Corticosteroids can increase intra-ocular pressure, in which increased intra-ocular pressure becomes a major riks factor for glaucoma. This study was aimed to association corticosteroid therapy with the incidence of glaucoma in children with nephrotic syndrome. Methods: This study was an observational analytic study with cross sectional design. Nephrotic syndrome samples were 23 children including 6 patients of steroid resistant nephrotic syndrome, 10 patiens of frequent relapse and 7 patiens of rare relapse. History of diagnosis of nephrotic syndrome and the use of corticosteroids obtained from medical records and data obtained from the examination diagnosis of glaucoma intra-ocular pressure using schiotz tonometry and optic nerve using Opthalmoskop. All samples were done before the examination consent inform the eye. Test statistical analysis used Chi-square and Fisher with the degree of significance p <0.05. Results: In this study found the incidence of glaucoma is 8.6% (2 patients) consisted of 16,6% (1 patient) steroid resistant nephrotic syndrome and 10% (1 patient) frequent relapses nephrotic syndrome. In this study found no positive the incident of glaucoma of rare relapse nephrotic syndrome Analysis of test results obtained the value of p= 1.000. Conclusion: There is no significant association corticosteroid therapy with the incidence of glaucoma in children with nephrotic syndrome. Keywords: corticosteroids, glaucoma, nephrotic syndrome, steroid resistance, frequent relapses, relapses are rare.

Item Type:Thesis (Undergraduate)
Subjects:R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services
Divisions:Faculty of Medicine > Department of Medicine
Faculty of Medicine > Department of Medicine
ID Code:37345
Deposited By:Ms Lutfiatun Heni
Deposited On:29 Nov 2012 11:41
Last Modified:29 Nov 2012 11:41

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