WAHYUNI, ANDI SRI and Muryawan, M. Heru and Radityo S, Adhie Nur (2012) HUBUNGAN ANTARA TERAPI KORTIKOSTEROID DENGAN KEJADIAN GLAUKOMA PADA ANAK DENGAN SINDROM NEFROTIK. Undergraduate thesis, Fakultas Kedokteran.
Background: Nephrotic syndrome is one of the most found kidney disease in children and corticosteroids are the primary form of therapy. Corticosteroids can increase intra-ocular pressure, in which increased intra-ocular pressure becomes a major riks factor for glaucoma. This study was aimed to association corticosteroid therapy with the incidence of glaucoma in children with nephrotic syndrome. Methods: This study was an observational analytic study with cross sectional design. Nephrotic syndrome samples were 23 children including 6 patients of steroid resistant nephrotic syndrome, 10 patiens of frequent relapse and 7 patiens of rare relapse. History of diagnosis of nephrotic syndrome and the use of corticosteroids obtained from medical records and data obtained from the examination diagnosis of glaucoma intra-ocular pressure using schiotz tonometry and optic nerve using Opthalmoskop. All samples were done before the examination consent inform the eye. Test statistical analysis used Chi-square and Fisher with the degree of significance p <0.05. Results: In this study found the incidence of glaucoma is 8.6% (2 patients) consisted of 16,6% (1 patient) steroid resistant nephrotic syndrome and 10% (1 patient) frequent relapses nephrotic syndrome. In this study found no positive the incident of glaucoma of rare relapse nephrotic syndrome Analysis of test results obtained the value of p= 1.000. Conclusion: There is no significant association corticosteroid therapy with the incidence of glaucoma in children with nephrotic syndrome. Keywords: corticosteroids, glaucoma, nephrotic syndrome, steroid resistance, frequent relapses, relapses are rare.
|Item Type:||Thesis (Undergraduate)|
|Subjects:||R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services|
|Divisions:||Faculty of Medicine > Department of Medicine|
Faculty of Medicine > Department of Medicine
|Deposited By:||Ms Lutfiatun Heni|
|Deposited On:||29 Nov 2012 11:41|
|Last Modified:||29 Nov 2012 11:41|
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