HUBUNGAN ANTARA HITUNG SEL CD4 DENGAN KEJADIAN RETINITIS PADA PASIEN HIV DI RSUP DR. KARIADI SEMARANG

Abstract

Background: HIV / AIDS causes deaths in the world. HIV (Human Immunodeficiency Virus) is a type of RNA retrovirus that attacks human immune system. AIDS (Acquired Immunodeficiency Syndrome)is the late stage of HIV infection where the human immune system is severely damaged and not able to fight diseases like cancer and other infections. One of the infections is retinitis that is caused by Cytomegalovirus or Toxoplasma infection, which can be happened if CD4 counts are decreased. Retinitis can cause blindness, which lower the quality of life. Aim: To know the relation between CD4 counts and retinitis. Methods: Observasional correlation study with retrospective design using medical record files. The samples were 61 medical record files from Internal Medicine Department of Dr. Kariadi Hospital Semarang, period of January 2007 – December 2011. Results: The total of HIV / AIDS patients in Dr. Kariadi Hospital Semarang period of January 2007 – December 2011 were 940 patients. There were 80 patients infected by Cytomegalovirus and/or Toxoplasm, but only 61 could be used as samples. It was found 15 (24.6%) had retinitis, 35 (57.4%) did not have retinitis, 11 (18%) were not known if they had retinitis or not. Based on chi-square statistic testing between CD counts < 50 cell / μL and retinitis in Dr. Kariadi Hospital Semarang, the p = 0.010, which the result had significant meaning if the p < 0.05. Conclusion: There is a relation between CD4 counts <50 cell / μL and retinitis in RSUP Dr. Kariadi Semarang. Key words: HIV/ AIDS, retinitis, CD4.