FAKTOR RISIKO KOLONISASI Staphylococcus aureus PADA NEONATUS

Abstract

Background: Staphylococcus aureus is a commensal bacteria that is numerous in the nasal cavity. Colonization of S.aureus in infants is found in the age 0-2 months and prevalence of infection by S.aureus in these ages is quite high. This study is aimed to explore risk factors for S.aureus colonization in neonates. Methods: This research was a cross-sectional study. Data obtained from the data record of infants 0-2 months of age at the posyandu in the Sub-district of Randusari, Mugasari, and Gajah Mungkur and by filling questionnaires. Subject were taken their nasal swab as samples. Then the nasal swab was examined in microbiology laboratory to identify S.aureus. Data was analyzed by Chisquare/Fisher-exact test then performed logistic regression. Results: The sample was 70 neonates. A positive S.aureus colonization was found in 38 samples. Prevalence of S.aureus colonization in neonates in this study was 54,3%. Vaginal route delivery was a risk factor of S.aureus colonization in neonates (PR = 6.424; 95% CI 1.726 to 23.918; p = 0.006) and length of stay over 2 days at health care institutions was also a risk factor of S.aureus colonization (PR = 4.448; 95% CI 1.414 to 13.989; p = 0.011). While prematurity (PR=1,231 ; 95% CI 0,620-2,443 ; p = 0.522) and non-exclusive breastfeeding (PR = 0,882 ; 95% CI = 0,344 – 2,262 ; p = 0.794) had no significant effect of S.aureus colonization in neonates. Conclusion: Prevalence of S.aureus colonization in neonates in this study is 54,3%. Vaginal route delivery and length of stay more than 2 days at health-care institutions is a risk factor S.aureus colonization in neonates, while prematurity and a non-exclusive breastfeeding had no effect on S.aureuscolonization in neonates. Key words: risk factors, S.aureus colonization, neonates