Korelasi Jumlah Folikel Ovarium dengan Konsentrasi Hormon Estrogen Mencit (Mus musculus) setelah Konsumsi Harian Tepung Kedelai selama 40 Hari

Abstract

Soybeans contains phytoestrogen that influence reproductive process. Phytoestrogen administration with chronical dosage along growth periode cause the neuroendocrine system disturbance. Commonly in human intake of phytoestrogen from soybeans or other soybeans product. So it is important to research beneficial and adverse effects of soybeans consumption with chronical dosage to reproductive process, particulary is corelation between the sum of ovarium follicles and the estrogen level of mouse (Mus musculus) after daily of soybeans along 40 days. The objective of this study was to know the corelation between the sum of ovarium follicle and the estrogen level of mouse, by experimental design. Adult female mice were use as experimental animal, divided into two groups, there were control and treatment. The group of treatment was administrated with 0,975 mg soybeans flour, it was contain ± 0,00156 mg phytoestrogen. The control group was administreted only drinking water. The result of this study shows were not significantly difference between control and treatment group. It concluded the corelation between the sum of ovarium follicles and the estrogen level were not influenced with daily consumption of fitoestrogen.