PERBEDAAN INFESTASI Cryptosporidium parvum ANTARA DIARE DAN TIDAK DIARE PADA PASIEN HIV/AIDS DI RSUP Dr.KARIADI SEMARANG

Abstract

Background : HIV/AIDS patients are vulnerable to infection. One of the disease caused by opportunistic infections is diarrhea. Cryptosporidium parvum is an obligate intracellular parasites, which cause prolonged diarrhea in people with HIV/AIDS. The objective of this study is to find out C. parvum colonization in HIV/AIDS patients with diarrhea and no diarrhea in Dr.Kariadi General Hospital, Semarang. Methods : This was an observational study with cross sectional retrieval, from December 2010 - May 2011 in the Internal Medicine ward of the Dr.Kariadi General Hospital, Semarang. Identification of oocist of C. parvum was performed by using Modified Ziehl Nielsen stain method from stool sample. Result : A total of 29 individuals with HIV/AIDS were collected from this study. There were 23 of 29 patients (79,3%) colonized by C. parvum, and 6 (20,7%) were not colonized by C. parvum. From patients who colonized by C. parvum consist of 6 (26,1%) with diarrhea and 17 (73,9%) with non diarrhea, and from patients without colonized by C. parvum consist of 2 (33,3%) with diarrhea and 4 (66,7%) with non diarrhea. Conclusion : There was no significant different between the colonization of C. parvum with diarrhea in HIV/AIDS patients in Dr.Kariadi General Hospital Semarang (p=1,00). This showed that both the state of diarrhea and non diarrhea, there was C. parvum colonized tendency. Clinical symptom like diarrhea was not a marker that a HIV/AIDS patient colonized by C. parvum.