FAKTOR- FAKTOR YANG MEMPENGARUHI KEBERHASILAN PENGOBATAN PADA PASIEN TUBERKULOSIS PARU DENGAN RESISTENSI OBAT TUBERKULOSIS DI WILAYAH JAWA TENGAH

Abstract

Background Indonesia nowadays have faced a new TB cases that more complicated and complex with MDR TB cases. World Health Organization have put Indonesia in level eight among high burden country with MDR TB in the world. TB with drug resistance is harder to cure, more expensive, more side effects, and low treatment result. This research aims to determine independent factors affecting successful treatment outcome of pulmonary tuberculosis patients with drug resistance in central java district. Methods This was an obsevational with cross sectional design study. Data collected with medical record. Case selections were taken from pulmonary TB patients with drug resistance based culturs on microbiology laboratory from Dr Ario Wirawan Hospital and Moewardi Hospital. Sample was taken from consecutive sampling with 45 patients from January 2006 to December 2009. The data analyzed by SPSS using chi square test with alternative fisher exact test, and lambda correlations test. Probability (p) is < 0,05 with 95% Confident Intervals. Result There was strong correlation between adherence to treatment (p = 0,00; r=0,72) and length of treatment (p=0,00;r=0,77) with successful treatment outcome and no significant differences between socio economic status (p=1,00), nutrition status (p=1,00), smoking habits (p=0,42), risk profession (p=0,19), distance between home and health facility (p=0,97) with successful outcome. Conclusion This study resulted adherence to treatment and length of treatment therapy have strong correlation with successful treatment outcome. To prevent spreading of these cases need a coordination between health institution and many sectors.