HUBUNGAN TINGKAT HIPERTENSI DENGAN KEJADIAN MIKROALBUMINURIA PADA ANAK OBESITAS USIA 12-14 TAHUN CORRELATION BETWEEN DEGREE OF HYPERTENSION AND MICROALBUMINURIA IN 12-14 YEARS OLD’S OBESE CHILDREN

Abstract

Background: Obesity in children is a risk for obese, cardiovascular disease, diabetes mellitus and renal dysfunction in adult. Hypertension may cause systemic endothelial dysfunction that can be diagnoses by the increase of microalbumin level in urine. Incidence of microalbuminuria in adult with hypertension is 8-15% and classified as incipient nephropathy. However, in children correlation between hypertension and microalbumin is poorly understood. Even though in adult a lot of study on correlation among obesity, hypertension and endothelial dysfunction are conducted, similar study in children is not extensively done. There is not any report on correlation between the degree of hypertension and microalbuminuria in obese children. Objective: To investigated correlation between the degree of hypertension and microalbuminuria in obese children with hypertension . Method: This study was a cross sectional study that conducted on a private junior high school at Semarang city in the period of Pebruary-April 2006. Obesity criteria was based on The International Obesity Task Force. Hypertension criteria was based on The Second Task Force on Blood Pressure Control in Children. Microalbumin urine level was define by immunoturbidimetry method. The level of microalbumin urine was expressed as g/mg creatinine. Microalbuminuria was defined the level of microalbumin urine > 20 ug/mg creatine. Results: From 403 children ,the incidence of obese was 18.3%, obese with hypertension was 6.3%. 28 children was found as subject and 2 was excluded, the average of systolic blood pressure was 139,0(SD=5,95) mmHg, diastolic blood pressure was 84,9 mmHg (SD=5,90) mmHg, the incidence of systolic hypertension was 15,4 %, borderline systolic was 23,1%, diastolic hypertension was 61,5%, mean urinary albumin excretion was 6,96 (SD=5,57) ug/mg kreatinin and microalbuminuria was found in 2 children (7,7%). There was no significant correlation between the degree of hypertension with microalbuminuria (p=0,5). Conclusion: There is no significant correlation between the degree of hypertension and microalbuminuria in 12-14 years old’s obese children. Key word: Obesity, hypertension, microalbuminuria, children