PENGARUH KADAR GLUKOSA DARAH SEWAKTU TERHADAP KELUARAN NEUROLOGIK PADA PENDERITA STROKE ISKEMIK FASE AKUT NONDIABETIK

Abstract

Background : An increasing of blood glucose levels is presumed to aggravate the neurological outcome of ischemic stroke patients. The research about association between increased blood glucose levels on nondiabetic patients with ischemic stroke and the neurological outcome measured by NIHSS is still small. Objective : To determine the effect of blood glucose levels on neurological outcome in nondiabetic patients with acute ischemic stroke. Methods : a cohort study with 32 nondiabetic patients with acute ischemic stroke who underwent treatment at Dr. Kariadi Hospital. The first blood glucose was drawn at 48 hours and the second at 72 hours after the onset of ischemic stroke. The neurological examination measured by NIHSS scale at 48 hours, 72 hours, and day 7 after the onset of ischemic stroke. The NIHSS score differences between 48 hours, 72 hours and day 7 were analyzed by Friedman test and Wilcoxon Post Hoc test. The correlation between blood glucose levels at 48 hours and 72 hours after the onset of ischemic stroke and neurological outcome were analyzed by Spearman correlation test. Results : There were differences in the mean NIHSS score at 48 hours, 72 hours, and day 7 with p value <0,0001. The Spearman correlation test between blood glucose levels at 48 hours and the patients neurological outcome at day 7 showed p value = 0,386. Conclusion : There is no correlation between blood glucose levels and the neurological outcome of the nondiabetic patients with acute ischemic stroke