PERBEDAAN EFEKTIVITAS ORAL HYGIENE ANTARA POVIDONE IODINE DENGAN CHLORHEXIDINE TERHADAP CLINICAL PULMONARY INFECTION SCORE PADA PENDERITA DENGAN VENTILATOR MEKANIK

Abstract

Background : Oral hygiene antiseptic was one of the manner can reduce incident Ventilator Associated Pneumonia (VAP) with reduce Clinical Pulmonary Infection Score (CPIS) in patients with mechanical ventilation. Chlorhexidin can prevent formation biofilm than povidone iodine. Objectives : This study was Performed to find out wether chlorhexidine 0,2 % was better than Povidone iodine 1 % on Clinical Pulmonary Infection Score in patients with mechanical ventilation Methods : An experimental study , as consecutive sampling on 32 subjects was devided in two groups (n=16). Povidone Iodine 1 % was administrated in first group and chlorhexidine 0,2 % in second group. Clinical Pulmonary Infection Score was determined before and Mann Whitney after treatment in each group: temperature, blood gas analysis, tracheal secretion, blood analysis and chest x-ray. Statistical analysis was performed with Wilcoxon test to compare CPIS, and correlative test to analyzed GC plaque and Spearman test to analyzed the correlation between GC plaque score and CPIS. Result : There were significant difference in the first group on CPIS (p<0,05), and no difference in the second group (p>0,05). The difference score before and after treatment in both group were significantly different (p=0,05). GC plaque score in chlorhexidine group were significantly different (p=0,0000). There were no correlation between GC plaque score and CPIS. Conclusion : Chlorhexidine 0,2 % is more effective oropharing decontaminated antiseptic that decreases CPIS than povidone iodine on patients with mechanical ventilation.No correlation between GC Plaque score with score of CPIS. Keywords : povidone iodine 1%, chlorhexidine 0,2 %, CPIS, mechanical ventilation, GCPlague