Kumoro, A.C. and Hasan, M. (2006) MODELLING OF SUPERCRITICAL CARBON DIOXIDE EXTRACTION OF ANDROGRAPHOLIDE FROM ANDROGRAPHIS PANICULATA LEAVES BY EMPLOYING INTEGRAL DESORPTION CONCEPT. In: FEIIC Seminar on Engineering and Technology, 4-5September 2006, Putrajaya, MALAYSIA.
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Mathematical formulation is necessary for the optimisation and scale-up of a separation unit such as the extraction of biomolecules from their natural resources. The objective of this work is to obtain a quantitative description of the supercritical carbon dioxide extraction (SCDE) of andrographolide from Andrographis paniculata leaves. This work presents the development of a mathematical model based on first order desorption rate of solute into supercritical fluid to describe the SCDE of andrographolide from Andrographis paniculata leaves. Numerical calculation was carried out using a commercial algebraic optimisation code, namely the MATLAB software. In this work, calculation was accomplished to obtain the adjustable parameter of the model using experimental data obtained from the SCDE of andrographolide at different operating temperature and pressure. The calculation results show that this model agrees very well with the experimental data. Therefore, this model is capable for the modelling of SCDE of andrographolide from Andrographis paniculata leaves.
|Item Type:||Conference or Workshop Item (Paper)|
|Uncontrolled Keywords:||modelling, supercritical carbon dioxide extraction, andrographolide, Andrographis paniculata, MATLAB|
|Subjects:||S Agriculture > S Agriculture (General)|
T Technology > TP Chemical technology
Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
|Divisions:||Faculty of Engineering > Department of Chemical Engineering|
Faculty of Engineering > Department of Chemical Engineering
|Deposited By:||Dr. Andri Kumoro|
|Deposited On:||05 Jun 2009 08:44|
|Last Modified:||05 Jun 2009 08:44|
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