Hubungan Paparan Debu Kayu dan Formaldehid dengan Faktor Risiko Terjadinya Karsinoma Nasofaring : (Studi Observasional pada Pasien Keganasan Kepala Leher di Klinik Telinga Hidung Tenggorok-Bedah Kepala dan Leher RS. Dr. Kariadi Periode 1 April 2008- 15 Juni 2008 )

Abstract

Background: The prevalence of Nasopharyngeal Carcinoma (NPC) in Indonesia is included in the biggest ten from other cancers in the body and number one at Otolaryngology-Head and Neck Surgery Department. Many researches about correlation between wood dust and formaldehyde exposure and NPC gave varied results. Objective: The aim of the study was to identify the correlation between occupational and environmental exposures to wood dust and formaldehyde and the development of NPC. Subject and Methods: The research, which was done at Otolaryngology ward, Radiotherapy installation and medical record installation of Dr. Kariadi Hospital, was a cross sectional study and the period of collecting data is from April 1st- June 15th 2008. 60 patients were sampled by using consecutive sampling. The research was measured through questionnaires. Tabulation of data used SPSS 15.0 for windows. The risk factors measured were occupational and environmental exposure to wood dust; formaldehyde in the form of dust, smokes, vapor, and diet. The data were tested by using chi-square method. Results: After testing the data by chi-square method, the results: wood dust occupational exposure (p=0,807); wood dust environmental exposure (p= 0,807); occupational exposure to formaldehyde in the form of dust, smokes, and vapor (p= 0,704); environmental exposure to formaldehyde in the form of dust, smokes, and vapor (p=0,515); exposure to dietary formaldehyde (p=0,251);Wood dust and formaldehyde exposure (p=0,643). Conclusions: There is no correlation between the increased risk of NPC and wood dust and formaldehyde exposure. Keywords: Nasopharyngeal carcinoma, risk factor, wood dust, formaldehyde.