PENGARUH PEMBERIAN GLISIN TERHADAP KADAR HEMATOKRIT REMAJA PUTRI DENGAN ANEMIA YANG MENDAPAT SUPLEMENTASI ZAT BESI

Abstract

Background: Nutritional anemia has bad effect to adolescent girls. Adolescent girls susceptible to nutritional anemia because of imbalancing between iron intake from food with increasing iron requirement. Anemic status determination can be shown by hematocrit level. Glycine, one of conditionally essential amino acids involved in hemoglobin biosynthesis, is predicted to enhance iron bioavailability that hematocrit level may be increased. This study had a purpose to prove that glycine addition on iron supplementation can affect the hematocrit level of anemic adolescent girls. Method: This true experimental study was Randomized Controlled Trial design. To the number of 20 adolescent girls with mild-moderate anemia were taken their blood speciment to measure first hematocrit value, then divided into two groups, control group (receive iron and placebo) and treatment group (receive iron and glycine). After 5 weeks treatment, they were examined again to measure the second hematocrit value. The data were processed by using SPSS 13.00 for windows, analyzed by using the Shapiro-Wilk test and Paired T-test. Results: The treatment group shows a statistically significance hematocrit level improvement, whereas the control group doesn’t show hematocrit level improvement. Conclusion: Glycine addition may raise anemic adolescent girls’s hematocrit level that receive iron supplementation. Key Words: glycine, adolescent girls, iron supplementation, hematocrit.