PENGARUH CARDIOPULMONARY BYPASS TERHADAP JUMLAH LEUKOSIT PADA OPERASI CORONARY ARTERY BYPASS GRAFT

Abstract

Background: Recently more cardiopulmonary bypass device is used on coronary artery bypass graft surgery procedure. The utilization of cardiopulmonary bypass device is increasing total leukocyte count which could be one sign the Systemic inflammatory response syndrome (SIRS). Purpose: to understand the effect of cardiopulmonary bypass device utilization on leukocyte count increase on coronary artery bypass graft surgery . Method: this is a retrospektive observational study on 18 patients that underwent coronary artery bypass graft surgery using Cardiopulmonary bypass device. Periphery blood samples for the leukocyte count was obtained pre-sternotomy or before surgery (Leukocyte 1) during CPB and 30th minute (Leukocyte 2) during CPB. Blood sample was count using automatic device. Paired t-test is used for statistical analysis (confidence interval < 0.05). Result: patient’s data characteristic will be presented as tables. This research shows significant results on Leukocyte 1 and Leukocyte 2, which leukocyte 1 has an average 6899.4 and the leukocyte 2 has an average of 8470. p = 0.000 ( p < 0.05 ) respectively. Conclusion: there is an increase on leukocyte count during CPB device utilization on 30th minute. Keyword: Leukocyte, cardiopulmonary bypass