HUBUNGAN ANTARA HIPERGLIKEMI DAN KEJADIAN KARSINOMA KOLOREKTAL DI RUMAH SAKIT UMUM PUSAT DR.KARIADI SEMARANG

Abstract

Background : Colorectal carcinoma is one of the most leading causes of death worldwide and in Indonesia. It is presumed that there is an association between hyperglycemia and the incidence of colorectal carcinoma. The purpose of this research is to know the association between hyperglycemia and the incidence of colorectal carcinoma in Kariadi Hospital. Method: This is a case-control study .The total samples of this research is 174 samples, and the samples are divided into two groups, the case group and the control group. The case group includes the patients who presented to Kariadi Hopsital between 2006-2009 and was diagnosed with colorectal carcinoma in any stages, while the control group includes those who have the other diseases in digestive system. All of the samples from each group are selected by simple random sampling. The number of appropiate sample according to the inclusion criterias is 101 for case and 73 for control. The Chi-Square Test is used to analyse the data. Result : The Chi–Square test showed that the value of p = 0.016, with OR : 2,763 ( 95% CI = 1,182- 6,457) Conclusion : Hyperglycemia is significantly associated with the increased risk of colorectal carcinoma. Keywords : colorectal carcinnoma, Hiperglycemia and colorectal carcinoma