PERBEDAAN KECEPATAN LISIS SEL HEPAR PADA TIKUS WISTAR DALAM MEDIA AIR TAWAR DAN TANAH : BERDASARKAN GAMBARAN HISTOPATOLOGI

Abstract

Background: Media in which the body is an important role in determining the speed of decay of the corpse. To know when the time of death can be seen from the description of the cell lysis histopathology body organs. This study aims to determine the speed difference hepar cell lysis in rats dead burried in the soil media and drowned in freshwater based on histopathology imaging. Methods: This was an experimental study using rats as a sample. The sample consisted of 10 male rats for the two treatment groups in which each study group consisted of five male rats. The first group would be buried in the soil media, while the second group would be drowned in fresh water. Each sample would be made one liver preparation with the lapse of time making each 12-minutes preparations. Then picture histopathological examination was performed to assess the structural changes in liver histology in rats. Any reading of the number of preparations carried out mutation analysis in 100 hepatocytes. Results: Results showed that the rate of cell lysis in fresh water and soil media, there was no significant difference. Conclusion: There is no significant difference between the speed of wistar rat liver cell lysis in fresh water and soil media on the basis of the description histopathology. So that way can not be used to present the long time of death. Keywords: Thanatologi, decomposition, cell lysis