SKRINING BARAN BIOAKTIF ANTI JAMUIR PADA BEBERAPA JENIS KARANG LUNAK DI PULAU PANJANG

Abstract

Soft coral is one of the most-potential - marine-organisms - as-a -source- bioactive substances. But, there are only few researches of bioactive substances from this organism conducted, because budget of the research is very high and lack of expert in this field. Screening of crude extract is the cheapest and simplest way to get the data of the potential organisms as source of bioactive substances. Aim of this research is to get data of potential species of soft corals as source of antifungal substances. Samples was collected by Scuba Diving. Then, it was extracted using methanol. Disk diffusion method was applied as antifungal assay again Aspergillus flavus and Saccharomyces cereviceae with four concentration i.e. TI (5 oWdisk), T2 (10 µg/disk), T3 (20 og/disk), T4 (40 µg/disk) and using methanol us a control. Five soft corals, include one species of genus Sarcophyton, two species of genus Lobophyton, one speCies of genus Sinularia and one species of genus Cladiella was utilized in this research. Methanol extract content of the soft corals vary from 2,0 % to 3,3 % from wet wight. Based on bioassay result, all of the soft corals contain extract which is inhibit the growth of Aspergillus flavus dan Saccharomyces cereviceae at 5 .tg/disk and 10 ogidisk. Result of regression analysis show that concentration of extracts and inhibition zone has positive correlation.