PENGARUH PEMBERIAN TEH HITAM TERHADAP KADAR SGOT DAN SGPT MENCIT BALB/C

Abstract

Background: Recently traditional medication have been developed, one of them is black tea. Previous research showed that black tea was able to prevent the formation of atherosclerosis. This research aim to complete the previous research by observing the effect of administration of black tea to SGOT and SGPT in balb/c mice. Method: This research used laboratory experimental method with post test-only control group design. Research sample were 15 balb/c mice that were divided into 3 groups randomly, each were given black tea with dose of 25,4 mg, 50,8 mg, and 101,6 mg each. Treatment was given for 30 days, then blood sampling and termination was carried out, afterwards the blood samples were examined. Data distribution was tested using Saphiro-Wilk, if data distribution is normal using oneway ANOVA test. Result: Mean SGOT on each group were P1=22,5, P2=21,9, and P3=37,9, then it were tested with oneway ANOVA test and the result was p=0.156 which mean that there was no significant difference among the groups. Mean SGPT were P1=7,8, P2=8,9, and P3=6,8, then it were tested with oneway ANOVA and the result was p=0.183 which mean that there was no significant difference among the groups. Conclusion: There was no significant difference to the SGOT and SGPT in balb/c mice at the administration of black tea until the dose of 101.6 mg each. Keywords: Black tea, SGOT, SGPT