PENGARUH FAKTOR SOSIAL EKONOMI TERHADAP KOLONISASI DAN POLA RESISTENSI Staphylococcus aureus PADA SISWA SD Penelitian di Tiga SD di Kota Semarang

Abstract

Background: Staphylococcus aureus is the main human pathogen, that can cause serious infections. This fact is supported with its ability to resist against antimicrobes. This germs usually live as asymptomatic colonies, especially in anterior nares of carriers. Carriage rate of S. aureus in children is higher than in adults. Social economy is assumed to be a factor that influences S. aureus’s colonization and its antimicrobial resistance. Methods: This research used cross-sectional design. Research sample were 127 students from elementary schools of Pandean Lamper, Kristen II YSKI, and Manyaran Semarang. Data were taken by nasal swab and interview. Nasal swab specimen then cultured on phenol red mannitol broth, Blood Agar; colonies that grew were then stained with Gram staining, catalase test, coagulase test, and susceptibility test. Data was analyzed using bivariate analysis, Prevalence Ratio, and multivariate analysis with SPSS 16.0 for Windows. Result: : From bivariate analysis, there were no significant p values for all variables (all p > 0,05). Multivariate analysis of education and crowding showed no significant influence on S. aureus’s colonization (p=0,090 and 0,147). That of education and income showed no significant influence on S. aureus’s antimicrobial resistance (p=0,092 and 0,425). Conclusion: Social economy factor, includes parent’s education level, parent’s occupation, parent’s income level, and crowding, didn’t influence S. aureus’s colonization and its antimicrobial resistance Keywords: Staphylococcus aureus, colonization, antimicrobial resistance, social economy factor