PERBANDINGAN LIDOKAIN DAN METOKLOPRAMID TERHADAP PENGURANGAN NYERI INJEKSI SAAT INDUKSI PROPOFOL

Utomo, Jombo (1999) PERBANDINGAN LIDOKAIN DAN METOKLOPRAMID TERHADAP PENGURANGAN NYERI INJEKSI SAAT INDUKSI PROPOFOL. Documentation. FAKULTAS KEDOKTERAN.

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Abstract

It have been Studied the comparation between lidocaine and metoclopramide in reducing pain on injection during propofol induction in Dr Kariadi General Hospital on Augus - October 1999. The aim of this Randomized Control Trial study was to prove does metoclopramide as effective as lidocaine in reducing pain on injection during propofol induction. 40 patients age between 15 - 60 years old, ASA I - II undergoing surgery with general anesthesi were divided into two groups. Group A recieved 0,1 mg/kg lidocaine while group B recieved 0,3 mg/kg metoclopramide. These mixture was injected intravenously with the speed of injection was 1 m1/5 second. The pain was evaluate with Visual Analouq Scale 0 -10. Blood pressure, heart rate and oxygen saturation was noted every minute for 3 minutes. There was no significant difference between lidocaine and metoclopramide groups in the intensity of pain (p0,05), the creep of pain also similar on both groups (p>0,05). There were no significant difference in the blood pressure, heart rate and oxygen saturation (p>0,05). We concluded that metoclopramide was as effective as lidocaine in reducing pain on injection during propofol induction. Telah dilakukan penelitian untuk membandingkan efektifitas antara lidokain dan metoklopramid dalam mengurangi nyeri injeksi saat induksi propofol di Rumah Sakit Dr Kariadi Semarang pada bulan Agustus - Oktober 1999. Tujuan penelitian ini adalah untuk membuktikan apakah metoklopramid sama efektifnya dengan lidokain dalam mengurangi nyeri injeksi propofol saat induksi. Penelitian dilakukan terhadap 40 orang penderita ,usia 15-60 tahun , ASA I-II, dengan rancangan penelitian Randomized Control Trial penderita dibagi menjadi 2 kelompok, kelompok A mendapatkan lidokain 0,1 mg/kg BB dan kelompok B mendapatkan metoklopramid 0,3 mg/kg BB yang dicampur dengan propofol 2 mg/kg BR Campuran tersebut kemudian disuntikan secara intravena dengan kecepatan 1 m1/5detik. Rasa nyeri yang timbul dinilai dengan VAS 0 - 10. Tekanan darah, Laju nadi dan Saturasi Oksigen dicatat tiap menit selama 3 menit berturut-turut. Hasil dan penelitian ini temyata intensitas nyeri antara kelompok lidokain dan metoklopramid berbeda tidak bermakna (p0,05), demikian juga derajat penjalaran nyeri kedua kelompok berbeda tidak bermakna (p0,05). Tekanan darah, laju nadi dan saturasi oksigen kedua kelompok juga berbeda tidak bermakna,(p>0,05) Kesimpulan metoklopramid sama efektifnya dengan lidokain dalam mengurangi nyeri injeksi propofol saat induksi.

Item Type:Monograph (Documentation)
Subjects:R Medicine > R Medicine (General)
Divisions:Faculty of Medicine > Department of Medicine
Faculty of Medicine > Department of Medicine
ID Code:22806
Deposited By:Mr UPT Perpus 5
Deposited On:07 Oct 2010 13:55
Last Modified:07 Oct 2010 13:55

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