PENGARUH INDUKSI SUKSINILKOLIN, PROPOFOL, DAN ATRAKURIUM TERHADAP TEKANAN DARAH DAN FREKUENSI DENYUT JANTUNG PADA SECTIO CAESARIA

Abstract

Background: Stress responses during operative and all of its results have to be concerned because it can increase mortality and morbidity during operative and post-operative. One of them is the hemodynamic changing, which can be seen on the changing of blood pressure and heart rate. The purpose of this study is to see the effect of Succinylcholine, Propofol, and Atracurium Induction on blood pressure and heart rate in caecarean section. Methods: This study is an observational analytic, used secondary data from medical record of RSUP Dr. Kariadi Semarang. The data is taken from 20 patients experiencing caesarean section procedure with ASA physical status I-II, age 20-35 years old, getting general anesthesia by rapid induction of Atracurium 5mg, Propofol 2-2.5 mg/kg, Succinylcholine 1 mg/kg, and Atracurium again 15 mg, and have no history of diabetes mellitus, hypertension, and stroke. The blood pressure and heart rate were measured before and five minutes after induction of general anesthesia. Result: The systolic blood pressure decreased not significantly at 5 minutes after induction ( 124.7(13.66) mmHg at 5 minutes after induction vs 125.7(10.86) mmHg before induction; p>0.05 ). The diastolic blood pressure increased not significantly at 5 minutes after induction ( 76.1(10.70) mmHg at 5 minutes after induction vs 74.1(11.96) mmHg before induction; p>0.05 ). The heart rate increased not significantly at 5 minutes after induction ( 95.7 (14.41) bites/min at 5 minutes after induction vs 90.6 (16.38) bites/min before induction ; p>0.05 ). Conclusion: The induction of Succinylcholine, Propofol, dan Atracurium can decrease systolic blood pressure, increase diastolic blood pressure, and increase heart rate which not significant. Keywords: Anesthesia, general anesthesia, blood pressure, heart rate.