AKURASI BIAKAN BACTEC PADA TBC PARU TERSANGKA DI BAGIAN PENYAKIT DALAM RSDK DAN BP 4 SEMARANG

Abstract

Tuberkulo.sis merupakan penyakit infeksi Mattis yang swath menjadi masabth dibidang ktaehatan tennama delam diagnostik, actmobatan, penularan, resistensi dan kontplikasinya, make dipestkan straitt nom diagnosis tiberkulosis yang cord, tepat sederbann dm murah. llama sekkar 3040% TBC paw yang dapat ditemukan BT A pada pcmenksaan mikroskopie langsung Osman pcngosatau ZN, sehingga dipmiukan cara pcmcriksamt biekart TBC yang kWh wneitil, den akurat. Talon dilakukan penelitian uji diagnostic akurasi biakan bactec pada 111C pant lersangka di Bagian penyakit dalam RSDK den BP4 Semarang sebum periodelanuari-Desember 1997. TUJUAN: Unluk mengetabui alcurest sensitivity, spcsifisilas biakan thrice dan kudnh pada petultrita TUC pans lersangka. DWAIN: trim scctional/ Mang Milan& SAMPEL:Penderita TBC pant tersangka di bapjan penyakit claim RSDK dan BP4. ANAL'S/X.. Denman label 2 x 2 wok uji diagnoslik 11ASIL: Selma periode lanuati-Desember 91 telah torkumpul 70 sampcI modest 113C paw lersangka, 2 (2,98%) sampel dikoluarkan (D0) kattna terkontaminats dan kering. Kobanyalcan 'readmits ski 45 (66,18%), Habakkuk beak math uSa preduktif 56 (82,35%) acbagai peketja kasar bump 15 (22,06%) dan (Mak bekerja II (gang (16,18%) Pemeasaan milouskopis langaung &Logan pcngccatan ZN slitcatukan kumsn pada 40 (58,112%) sodiaan (13TX 4), dengan pembiakan Kudoh didapatkan 51 (75%) sediaan tundra rnikobaktaium (biakan Scdangken (Langan pembenMan modia Baotec dapat ditsobsi kurnan ntikobaktmium schanyak 56 (82,35%). Sensitivity biakan BAMC 94,12% dan kudoh 92,50%, Spcsiasitas biakan bastes, sebesar 52,91% kudoh 50,00%. Aktirasi bactec 83,82%, nilai roma gnsitif 85,72% eedangkan MIS tame! negatithya 75%.Waktu perturnbutout Lunen pada media bactec sebagjan Issas minced kedua. (55,36M) KESIMPULAN: •Sensitivitaa Hahn bactec linggi 94,12%, akwasinya bails 83,82% namun spcsiOsilasnya mulls rendah 52,94%. 'Waktu perturnbuhan koman pada media ludas kcbanyalon minggu pajama dan %dna elliakan baste° lath sooting deli pemmiksaan milupslaupis humming (moguls Laken katinb Mikan hactec dapat dipartimbengkan schagai motode Stoma& ',comma unntk mendiagno rie tubcaulosis pans scans ceps dan aktnet. •Karma ketorbatasaan penclilimini, maka pada dilakukan tiji diagnostic kultur bactee down sampel yang lcbilt banyak don spectrum 'skulk lebih Mat Tuberculosis (113) is an ancient infection disease which is still considered as a wand problem, especially in underdeveloping countries. The main problem arc diagnostic, prevention, management and control tehniques. The diagnostic of tuberculosis was based on clinical aspect and acid fast bacilli examination. It is important found sputum acid fast bacilli (MB) by microscopic examination using the direct smear or culture. She BACTEC TB System has been reported to be valuable for the rapid detection of mycobacteria clinically important. OBJECTIVE : This study was proposed to and out sensitivity, and spesificity of BACTEC TB system culture in clinically tuberculosis. MATERIAL Sixty eight samples of sputum with give result positif and negatif for direct microscopic examination acid fast bacilli (AFB). METHODS : of this study is cross sectional. STATISTICAL METHODS: two by two table for diagnostic test analysis. RESULT: A total of 68 subjects range age 15-70 year, consisting of 23 ( 33,82%) female and 45 (66,18%) male. 8Z35% subject arc in productive age's and more than 22,06% subject as a labor. Examination of sputum AFB by direct smear showed posilif result 40 (58,82%) and conventionale methods culture (KUDOH) wich give result 51 (75%), while the use of BACTEC TB system recoveries of significant mycobacteria in 56(82,35%). The BACTEC Tb system culture sensitivity 94,12% while KUDOH 92,50%, BACTEC spesificity 52,94% acuracy 83,82%, positive predictive value 85,72% and negative predictive value 75%. Time required for isoladon mycobacteria an BATEC TB system most for two week. CONCLUSION: The BACTEC TB system culture sensitivity arc 94,12%, acurarY 83,82% but spesificity only 52,94%. Most of micobactetia growth in second week for BACTEC TB system. The BACTEC TB system culture for recovery micobacteda faster than cotwentionale methods. Many limitation of this study that we require for continuoing studies with more number subject and wide's clinic mammon.