FAKTOR RISIKO KEJADIAN MORTALITAS PADA PASIEN DENGAN BAKTERIEMIA DI NEONATAL INTENSIVE CARE UNIT (NICU) RUMAH SAKIT DR. KARIADI 1 JANUARI 2004 – 31 DESEMBER 2005

Abstract

Background : Bacteremia in neonate is a life-threatened condition and requires the right management immediately. Primary identification of mortality risk factor in bacteremia neonate is needed to avoid mortality occurrence. The objective of this study was to identify the risk factor of mortality in bacteremia patients at NICU of dr Kariadi hospital. Method : A cross sectional study was carried out retrospectively from 33 medical records of bacteremic patients hospitalized at NICU of dr Kariadi hospital from January 2004 to December 2005.Bivariate analysis with Chi square and fisher tes is required to test the data. Interference of some variables was analyzed by logistic regression. Result : It was found that preterm gestation was a significant risk factor of mortality (p 0,001 ; PR 21,429; 95% CI 2,275 – 201,865 ), as well as low birth weight ( p 0,049 ; PR 4,286; 955 CI 0,968 – 18,973 ). Meanwhile sex, age, asphyxia history, bacteria species, bacteria resistance to gentamycin and cefotaxim, nursery term and inappropriate antibiotic admission according blood culture result were not risk factors of mortality. Logistic regression analysis shows that preterm gestation had a significant result. It was found that preterm gestation was a risk factor in logistic regression analysis (p 0,07). Conclusion : Preterm gestation and low birth weight are independent risk factor for occurrence of mortality in bacteremia neonate. Key words : mortality, bacteremia, risk factor