UJI BANDING EFEKTIVITAS BUGENFIL (Bougainvillea glabra Choicy.) 100% DAN KETOKONAZOL 2 % SECARA INVITRO TERHADAP PERTUMBUHAN Candida albicans PADA KANDIDIASIS VAGINALIS

Abstract

Background: Candidiasis is infection which cause of Candida. Ketoconazole is an effective antifungal. Bougainvillea glabra Choicy. is an traditional drug to treatment of leucorrhea. Objective: To compare the effectiveness of 100% Bougainvillea glabra Choicy. versus 2% ketoconazole in tratment of vaginal candidiasis. Method: This study was done by a laboratory experimental. As samples were the result of (+)Candida albicans inoculations at SDA medias. These were made the solution equal to 0,5 Mc Farland. 0,1 cc of solution was cultivated on the SDA media supplemented with 100% Bougainvillea glabra Choicy. and 2% ketoconazole. Incubated at 370 C for 2 days and looked those growth. If grow yeast on SDA media thus the result is (+) Candida albicans, and if don’t grow yeast on SDA media thus the result is (-) Candida albicans. The difference proportion of growth was analyzed by chi-square test with degree of signifance of p<0,05. Result: 30 medias of SDA which contained 100% Bougainvillea glabra Choicy.,30 medias were found (+)/positive for growth Candida albicans. Meanwhile, 30 medias which contained 2% ketoconazole, 15 medias were found positive and 15 medias were found negative. The result of the chi-square test is significant ( p= 0,000 ). Conclusion: 100% Bougainvillea glabra Choicy. is uneffective in inhibiting the growth of Candida albicans in kandidiasis vaginalis whereas 2% ketoconazole is effective. Key words: Vaginal candidiasis, Candida albicans, 100% Bougainvillea glabra Choicy., 2% Ketoconazole.