PENGARUH PEMBERIAN MINYAK Pandanus conoideus TERHADAP DERAJAT PARASITEMIA MENCIT Swiss YANG DIINFEKSI Plasmodium berghei ANKA

AMELYA P.S, MERRY (2006) PENGARUH PEMBERIAN MINYAK Pandanus conoideus TERHADAP DERAJAT PARASITEMIA MENCIT Swiss YANG DIINFEKSI Plasmodium berghei ANKA. Undergraduate thesis, Faculty of Medicine.

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Abstract

Background : Malaria is a disease with high mortality and morbidity rate. Although there was controlling programs, malaria still being a serious problem in the tropical country. Pandanus conoideus ( Red fruit ) is a traditional herbal medicine that consists of elements which can stimulate the human immune system by increasing the activities of T helper lymphocyte to eliminate the parasitizied erythrocyte. This experiment was meant to know the effect of Pandanus conoideus on the parasitemia degree of Plasmodium berghei ANKA infected Swiss mice. Method : The design of this study was an experimental study using The Post Test Only Control Group Design. This study used 14 healthy female mice, ages between 8 – 12 weeks, weight between 25 – 30 gram. The mice were divided randomly into 2 groups, 1st Group I ( Control group ) and 2nd Group ( Treated group ) which were given 0,05 cc of Pandanus conoideus oil orally every day for 6 days. Both of groups were infected through intraperitoneal injection with mice blood which contained Plasmodium berghei 1 x 104 parasite for 0,01cc. After injection, the numbers of parasitemia degree were thicked using thin blood smear analysis Result : The parasitemia degree on the treated group was less than the control group on the 1st day, 3rd day and 5th day. The mean difference on the 1st day p=0,001, 3rd day p=0.000, and at the 5th day p= 0,001. Conclusion : Infusion of Pandanus conoideus can significantly reduce the parasitemia degree of Plasmodium berghei ANKA infected Swiss mice. Keywords : Pandanus conoideus, Parasitemia degree, Plasmodium berghei ANKA

Item Type:Thesis (Undergraduate)
Subjects:R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:Faculty of Medicine > Department of Medicine
Faculty of Medicine > Department of Medicine
ID Code:21284
Deposited By:Ms Lutfiatun Heni
Deposited On:28 Aug 2010 08:29
Last Modified:28 Aug 2010 08:29

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