PENGARUH PEMBERIAN VIRGIN COCONUT OIL TERHADAP KADAR KOLESTEROL HIGH DENSITY LIPOPROTEIN (HDL) SERUM TIKUS WISTAR SETELAH DIINDUKSI ATEROGENESIS

Abstract

Background: Many people use Virgin Coconut Oil (VCO) to reduce the insidence of atherosclerosis, cardiovascular disease; prevent body from bacterial, viral, and fungal infection, and also can boost immune system againts infections. But, in the other side, many people still think that coconut oil is not good for health because it contains high cholesterol. The objective of this study is to investigate the effect of virgin coconut oil on HDL serum level of wistar rats which were inducted atherogenesis Methods: This study was an experimental study with post test only control group design. The sample were 16 male aged 20 weeks wistar rats, that rendomly allocated into 2 groups. The first group was control group (C), and the second group was treatment group (T). Collected data were HDL serum. The difference of measured parameters between groups were analyzed by indipendent t-test . Data were analyzed by SPSS 13.0 for windows Result: Treatment group is 105,61 ± 1,80 mg% were higher than the control group HDL serum level was 79,648 ± 1,44 mg%. Independent T test between control group and treatment group was significantly different (p=0,00, p<0,01). Conclusion: HDL serum of rats that receive virgin coconut oil 2 mg for 4 weeks were significantly higher than control group. Keywords: Virgin coconut oil, HDL cholesterol serum.