Efek Rebusan Daun Tapak Dara pada Dosis dan Frekuensi yang Berbeda terhadap Kerusakan dan Akumulasi Glikogen pada Hepar Mencit (Mus musculus)

Abstract

The aim of this research was investigated the effect of boiled -Vinca rosea leaf for hepar and glycogen accumulation in Mus musculus hepatocyts on several dosages, frequencies and the interaction of dosagesfrequencies. The research was using factorial experiment with Complete Randomize Design and continued with Duncan test at 5% level. The result of this experiment was indicated that there was significant on the difference dosage. The higher dosage boiled- Vinca rosea leaf that given into Mus musculus, it would make the more hepatocyts damage. Hepatocyt injury was indicated with swollen until atrophy cell with glycogen accumulation in the cytoplasm of hepatocyt.